Post-Digital Research - Editorial

Although in many ways the post-digital “sucks but is useful” as Florian Cramer notes in his contribution, this issue of A Peer-Reviewed Journal About Post-Digital Research takes it to be a serious concept that deserves our critical attention. The journal issue is divided into three sections, that address the term itself, its genealogy and wider connotations, as well as its potential usefulness across different fields (including art, acoustics, aesthetic theory, political economy and philosophy). Given that the term comes from practice, it also addresses how the post-digital potentially operates as a framework for practice-based research that relate to material and historical conditions

Machine Research - Editorial

This publication is about Machine Research – research on machines, research with machines, and research as a machine. It thus explores machinic perspectives to suggest a situation where the humanities are put into a critical perspective by machine driven ecologies, ontologies and epistemologies of thinking and acting. It aims to engage research and artistic practice that takes into account the new materialist conditions implied by nonhuman techno-ecologies. Articles include new ontologies and intelligence such as machine learning, machine reading and listening, systems-oriented perspectives to broadcast communication and conflict, the ethics and aesthetics of autonomous systems, and other post-anthropocentric reconsiderations of materiality and infrastructure

Datafied Research - Editorial

This issue of APRJA examines the implications of datafication for research. The articles provide responses that outsmart and outplay the logic of capturing everything applied by the corporate as well as scientific communities. Each in their own way they address the complexity af 'capture', and examine datafication’s connection to commodification (and even to zombification), and examine alternatives such as obfuscation in order to know and unknow things at different registers and scales – from the grain of data to big data, the materiality of data and the politics of data structures, or in other ways afforded by emergent practices of datafied research

Pulmonary apelin levels and effects in rats with hypoxic pulmonary hypertension

SummaryBackgroundThe peptide apelin is localised in the vascular endothelium and highly expressed in pulmonary tissue. The aim of this study was to investigate whether apelin could be a potential lung-derived plasma marker for pulmonary hypertension, and study the effect of apelin in pulmonary arteries.MethodsApelin protein levels were measured in the lung, right ventricle, and plasma from normoxic and chronic hypoxic rats with pulmonary hypertension. Isolated intrapulmonary arteries were mounted in microvascular myographs and the effect of apelin investigated. Finally, the distribution of apelin receptors in pulmonary tissue was visualised by immunohistochemistry.ResultsTotal pulmonary apelin content was not changed by hypoxia. Right ventricular apelin concentrations and content were lower than in the lung, but increased substantially in hypoxia in correlation with right ventricular pressure. Plasma apelin did not reflect pulmonary or right ventricular apelin levels. In pulmonary arteries from normoxic rats, apelin inhibited vasoconstriction to endothelin-1 and angiotensin-II. However, in arteries from hypoxic rats, apelin failed to inhibit contraction to angiotensin-II and endothelin-1. No difference in immunoreaction for apelin receptors was found in lung sections and arteries from normoxic versus chronic hypoxic rats.ConclusionsApelin changes in the right ventricle seem more specific for pulmonary hypertension than do changes in pulmonary tissue, which does not speak in favour of apelin as a lung-derived marker for this disease. During normoxic conditions, apelin has a modulating effect on vasoconstriction which is lost in chronic hypoxia. This may reflect alterations in the signal transduction downstream of the apelin receptor

A Peer-reviewed Newspaper About_ Datafied Research

An examination of the implications of datafication for research: to investigate and propose actions that push against the limits of today’s pervasive quantification of life, work, and play. Publication resulting from research workshop at School of Creative Media, City University of Hong Kong, organised in collaboration with School of Creative Media, City University of Hong Kong, and transmediale festival of art and digital culture, Berlin

A Peer-reviewed Newspaper About_ Excessive Research

Research on machines, research with machines, and research as a machine. Publication resulting from research workshop at Exhibition Research Lab, Liverpool John Moores University, organised in collaboration with Liverpool John Moores University and Liverpool Biennial, and transmediale festival for art and digital culture, Berlin

A Peer-reviewed Newspaper About_ Machine Research

About research on machines, research with machines, and research as a machine. Publication resulting from research workshop at Brussels World Trade Center, organised in collaboration with Constant, Association for Arts and Media, Brussels, and transmediale festival for art and digital culture, Berlin

A Peer-reviewed Newspaper About_ Post-digital Research

Post-digital Research addressed the messy and paradoxical condition of art and media after digital technology revolutions. Publication resulting from research workshop at Kunsthal Aarhus, in collaboration with Kunsthal Aarhus, and trans,ediale festival for art and digital culture, Berlin